Lower extremity peripheral artery disease (PAD) affects approximately 15% of community dwelling men and women age 65 and older and will be increasingly common as the U.S. population survives longer with chronic disease. People with PAD have an increased risk of heart disease and stroke and also suffer from functional impairment and mobility loss. Research in the Division of General Internal Medicine and Geriatrics focuses in part on identifying clinical characteristics that predict mobility loss in patients with PAD. This information is used to develop new interventions to improve functional performance and prevent mobility loss in people with PAD. In addition, the Division is active in leading clinical trial research to improve functioning and prevent mobility loss in PAD. Further information about clinical trials can be found elsewhere on this web page. All of our research in peripheral artery disease aims to prevent adverse outcomes, improve quality of life, and prevent PAD in the large and growing number of people who suffer from PAD.