Stephen D Persell, MD/MPH

Associate Professor
Division of General Internal Medicine and Geriatrics
750 N Lake Shore Drive, 10th Floor
Chicago, IL 60611

About this Investigator

I am a health services researcher and primary care internist. My research involves the design, implementation and evaluation of electronic health records-based quality improvement tools, practice redesign techniques and methods for clinician performance measurement. I have performed multiple studies using data from clinical information systems to assess various aspects of cardiovascular disease, hypertension and preventive care. In my AHRQ-sponsored career development award, I performed a randomized trial that demonstrated positive effects of delivering patient-directed CVD prevention messages on statin prescribing and cholesterol control. I currently lead two large randomized intervention studies testing ways to use health information technology and care team change to improve care. The first is a NIH-funded R01 study examining the impact on hypertension control of strategies using IT-supported medication management tools and nurse-led care redesign in 12 community health centers among patients using 3 or more medications. This study is examining if using low-literacy-appropriate educational strategies embedded in an electronic health record with and without a nurse educator improves uncontrolled hypertension, medication discrepancies, and medication adherence. The second is an AHRQ-funded trial of health IT-supported patient identification and lay outreach to promote appropriate preventive cardiology practices at community health centers in two states.


Brigham & Women's Hospital
Harvard University

Lab Members

Elisha Friesema
Sr Program Administrator and Research Operations Manager
Tiffany Brown
Research Project Manager
John Wagner
Research Study Assistant